The scientific principle is that
If a theory disagrees with experiment then it is wrong.

Derivable from this is that
Mathematics is the language in which theories are written, and
The assumptions of a theory must be testable by experiment, and
The the corpus of human knowledge is understandable through the scientific method.

Furthermore, my priors have established several theories through experiment which I have studied critically.
I believe that Newton's Laws will always hold when is not concerned with the very small or very large or very fast.
I believe that Lagrangian Mechanics is a more efficient way to do Newtonian calculations in complex systems.
I believe that Quantum Mechanics holds for things which are very small.
I believe Relativity holds for things which are moving very fast.
I believe Quantum field theory describes things which are both very small and at high energies.
I believe Maxwell's Equations describe electromagnetism at large scales while Quantumelectrodynamics adds validity for the atomic and subatomic scale.
I believe that all biological processes happen through chemical reactions.
I believe quantum mechanics gives a good description of these reactions.
I believe that organisms often organize themselves into societies which eventually supplant those organisms as organisms themselves.
I believe reality exists apart from my perception of it.
I believe a great many things, but that faith is always tempered by experiment.
I can have no faith in the untested or the untestable.
My temple is the lab, the library, and the forest where I probe to gain a greater understanding of the Truth.